Gagosian is a contemporary art gallery owned and directed by Larry Gagosian. The gallery exhibits some of the most influential artists of the 20th and 21st centuries. There are 16 gallery spaces: five in New York; three in London; two in Paris; one each in Basel, Beverly Hills, San Francisco, Rome, Athens, Geneva and Hong Kong.

In spring of 2000, Gagosian became an international gallery with the opening of a Caruso St John-designed space on Heddon Street in Piccadilly, London, then the largest commercial art gallery in the city.[5] The UK gallery inaugurated its exhibitions program with a performance by the Italian artist Vanessa Beecroft, followed by an exhibition of works by Chris Burden. In September 2000, in New York, Gagosian held the Hirst show, Damien Hirst: Models, Methods, Approaches, Assumptions, Results and Findings.

A second London Gallery, also designed by Caruso St John, on Britannia Street, opened in May 2004 with a paintings and sculpture show by Cy Twombly. Comparable to the Chelsea exhibition space in size, this addition was then the largest commercial art gallery in London.[5] It accommodated large sculpture, video pieces and installations such as Martin Kippenberger’s show, The Magical Misery Tour, Brazil. The Heddon Street location closed in July 2005, and a new storefront space on Davies Street opened simultaneously with an exhibition of Pablo Picasso prints.

To complement the West 24th Street gallery, a Richard Gluckman designed space on West 21st Street opened in October 2006. A joint exhibition with the 24th Street gallery, Cast a Cold Eye: The Late Works of Andy Warhol, launched Gagosian Gallery’s second location in Chelsea and third location in New York. In 2009, the 21st Street gallery held an exhibition of Pablo Picasso’s late works entitled Mosqueteros, curated by Picasso historian John Richardson.